Papers

Papers:

  1. Barnes JW, Kucera ET, Tian L, Mellor NE, Dvorina N, Baldwin Iii WW, Aldred MA, Farver CF, Comhair SA, Aytekin M, Dweik RA. BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH. Am J Respir Cell Mol Biol. 2016 May 17. DOI:10.1165/rcmb.2015-0402OC. CLICK TO DOWNLOAD PDF
  2. Inanc MT, Karadavut S, Aytekin M, Duran AO, Derya M, Akpek M, Sahin O, Kalay N, Karaca H, Ozkan M, Inanc M. The relationship between plasma hyaluronan levels and anthracycline-related cardiotoxicity in breast cancer patients. Int J Cardiol. 2016 May 13;218:246-251. doi: 10.1016/j.ijcard.2016.05.054. CLICK TO DOWNLOAD PDF
  3. Pınar Altın, Jarrod Barnes Metin Aytekin*: Biomarkers in Pulmonary Hypertension. J. Harmoniz. Res. Med. And Hlth. Sci. 2016, 3(1):55-65. CLICK TO DOWNLOAD PDF
  4. Nihat Kalay, Mehmet T. İnanç, Deniz Elçik, Fatma Kılıç,Göktuğ Savaş, Kenan İzgi and Metin Aytekin*: Diagnostic Role of Plasma and Hair Trace Elements in Coronary Atherosclerosis. Trace Elements And Electrolytes.  2016, 33:1: 1-7 CLICK TO DOWNLOAD SOON. *correspond author
  5. Aytekin M, Tonelli AR, Farver CF, Feldstein AE, Dweik RA: Leptin deficiency recapitulates the histological features of pulmonary arterial hypertension in mice. The International Journal of Clinical and Experimental Pathology. 2014;7(5):1935-1946. CLICK TO DOWNLOAD PDF
  6. Derya M, Yilmaz I, Aytekin M*: The Role of Extracellular Matrix in Lung Diseases. Biology and Medicine. 2014;6(2):doi:10.4172/0974-8369.1000200. CLICK TO DOWNLOAD PDF *correspond author
  7. Kalay N, Elcik D, Savaş G, Altın P, Şakalar Ç, Kaya Ö, Aytekin M*: Elevated Hyaluronan Levels in Patients with Rheumatic Mitral Stenosis and Pulmonary Arterial Thromboembolism. Heart, Lung and Circulation. 2014;23:649-654. CLICK TO DOWNLOAD PDF*correspond author
  8. Aytekin M*, Lauer ME, Comhair SA, Loftis J, Tian L, Farver CF, Hascall VC and Dweik RA: Modification of Hyaluronan by Heavy Chains of Inter-Alpha-Inhibitor in Idiopathic Pulmonary Arterial Hypertension. J. Biol. Chem. 2014;289:6791-6798. CLICK TO DOWNLOAD PDF *co-first author
  9. Heresi GA, Aytekin M, Hammel JP, Wang S, Chatterjee S, Dweik RA: Plasma interleukin-6 adds prognostic information in pulmonary arterial hypertension. Eur Respir J. 2014;43(3):912-4. CLICK TO DOWNLOAD PDF
  10. Sakalar C, Yuruk M, Kaya T, Aytekin M, Kuk S, Canatan H.:Pronounced transcriptional regulation of apoptotic and TNF-NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells. Mol Cell Biochem. 2013 basım aşamasında. CLICK TO DOWNLOAD PDF
  11. Kalay N, Elcik D, Canatan H, Kaya MG, Yarlioglues M, Ohuzhan A, Dweik RA, and Aytekin M*: Elevated plasma hyaluronan levels in pulmonary hypertension. Tohoku J. Exp. Med. 2013;230,7-11. CLICK TO DOWNLOAD PDF *correspond author
  12. Adriano R. Tornelli, Sarah Haserodt, Metin Aytekin, and Raed A. Dweik: Nitric oxide deficiency in pulmonary hypertension: Pathobiology and implication for therapy. Pulmonary Circulation. 2013;4(1):20-30. CLICK TO DOWNLOAD PDF
  13. Ayten O, Tas D, Demirer E, Okutan O, Ciftci F, Aytekin M, Uysal A, Kartaloglu Z.: Angiopoietin 2 levels in serum and bronchial lavage fluids and their relationship with cancer stages in lung cancer patients. Thoracic Cancer. 2013;4(1):20-26. CLICK TO DOWNLOAD PDF
  14. Ersin Demirer, Metin Aytekin, Atilla Uysal, Dilaver Taş, Oğuzhan Okutan, Turgut Öztutgan, Zafer Kartaloğlu, Niyazi Ümit Çitici: The “When and Why” Behind Failure of a Fiberoptic Bronchoscopy. The Annals of Eurasian Medicine. 2013;1(2): 31-4. CLICK TO DOWNLOAD PDF
  15. Tonelli AR, Aytekin M, Feldstein A, and Dweik RA.: Leptin levels predict survival in pulmonary arterial hypertension. Pulmonary Circulation. 2012;2(2):188-93. CLICK TO DOWNLOAD PDF
  16. Aytekin M., Dweik RA.: Nitric oxide and asthma severity: towards a better understanding of asthma phenotypes. Clinical and Experimental Allergy. 2012;42:614-616. CLICK TO DOWNLOAD PDF
  17. Metin Aytekin., Aulak Kulwant Singh, Sarah Haserodt, Ritu Chakravarti, Joseph Cody, Omar A. Minai, Raed A. Dweik: ABNORMAL PLATELET AGGREGATION IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION: ROLE OF NITRIC OXIDE. Am J Physiol Lung Cell Mol Physiol. 2012;302:L512-L520. CLICK TO DOWNLOAD PDF
  18. Kalay N., Aytekin M., Kaya MG., Ozbek K., Karayakali M., Sogut E., Altunkas F., Ozturk A., Koc F.: The relationship between inflammation and slow coronary flow: red cell distribution and serum uric acid levels Inflamasyon ve yavaş koroner akım ilişkisi: kırmızı hücre dağılımı ve serum ürik asid seviyesi. Turk Kardiyoloji Dernegi Arsivi. 2011;39(6):463-468. CLICK TO DOWNLOAD PDF
  19. Mashir A, Paschke KM, van Duin D, Shrestha NK, Laskowski D, Storer MK, Yen-Liberman B, Gordon SM, Aytekin M and Dweik RA.: Effect of the influenza A (H1N1) live attenuated intranasal vaccine on nitric oxide (FENO) and other volatiles in exhaled breath. J. Breath Res. 2011; 5, p1-6. CLICK TO DOWNLOAD PDF
  20. Heresi GA, Tang WWH, Aytekin M, Hammel J, Hazen SL and Dweik RA: Sensitive cardiac troponin I predicts poor outcomes in pulmonary arterial hypertension. European Respiratory Society. 2011.Accepted 11-Aug-2011. CLICK TO DOWNLOAD PDF
  21. Çaylak E., Aytekin M*: An Industrial risk: Beryllium. Journal of Clinical and Experimental Investigations. 2011;3(1):141-148. CLICK TO DOWNLOAD PDF *correspond author
  22. Koc S, Aytekin M, Kalay N, Ozcetin M, Burucu T, Ozbek K, Celik A, Kadi H, Gulturk S, Koc F.: The effect of adenotonsillectomy on right ventricle function and pulmonary artery pressure in children with adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol. 2011;76:45-48. CLICK TO DOWNLOAD PDF
  23. Aytekin M., Dweik RA. Low molecular mass of hyaluronan was detected in PASMCs from the patients with idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2011; 300: L148. CLICK TO DOWNLOAD PDF
  24. Haserodt S., Aytekin M., Dweik RA. A Comparison of the Sensitivity, Specificity, and Molecular Weight Accuracy of Three Different Commercially Available Hyaluronan ELISA-like Assays. Glycobiology. 2011 Feb;21(2):175-83. CLICK TO DOWNLOAD PDF
  25. Aytekin M, Çaylak E. Pulmonary Arterial Hypertension: Past, Present and Future. J Tub Thorax. 2010; 58(1): 100-107. CLICK TO DOWNLOAD PDF
  26. Heresi GA, Aytekin M, Newman J, DiDonato J, and Dweik RA: “Plasma levels of high-density lipoprotein cholesterol and outcomes in pulmonary arterial hypertension” American Journal of Respiratory and Critical Care Medicine. Vol 182. pp 661–668, 2010 CLICK TO DOWNLOAD PDF
  27. Heresi GA, Aytekin M, Newman J and Dweik RA: “CXC-chemokine ligand 10 in idiopathic pulmonary arterial hypertension: marker of improved survival” Lung, 2010; 188: 191-197. CLICK TO DOWNLOAD PDF
  28. Aytekin M, Çaylak E. Hyaluranon and the importance of Hyaluronan in diagnosis and treatment. J Tub Thorax. 2009; 57(3): 356-364. CLICK TO DOWNLOAD PDF
  29. Aytekin M, Comhair SA, de la Motte C, Bandyopadhyay SK, Farver CF, Hascall VC, Erzurum SC, Dweik RA. High levels of hyaluronan in idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2008; 295(5): p. L789-99. CLICK TO DOWNLOAD PDF
  30. Grob NM, Aytekin M , and Dweik R A. Biomarkers in exhaled breath condensate: a review of collection, processing and analysis. J. Breath Res. 2- (2008) Sep 8, 1-18. CLICK TO DOWNLOAD PDF
  31. Caylak E, Aytekin M*, Halifeoglu I. Antioxidant effects of methionine alpha-lipoic acid, N-acetylcysteine and homocysteine on lead-induced oxidative stress to erythrocytes in rats. Experimental and Toxicologic Pathology. 2008 Nov 20; 60-289-294. *correspond author. CLICK TO DOWNLOAD PDF
  32. Aytekin M, Vinatzer U, Musteanu M, Raynaud S, Wieser R. Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5′-ends. Gene.2005 Aug 15; 356:160- 8. CLICK TO DOWNLOAD PDF
  33. Wieser, R., Schreiner, U., Pirc-Danoewinata, H., Aytekin, M., Schmidt, H.H., Rieder, H., and Fonatsch, C.: Interphase fluorescence in situ hybridization assay for the detection of 3q21 rearrangements in myeloid malignancies.Genes, Chromosomes, Cancer.(2001) 32, 373-380. CLICK TO DOWNLOAD PDF
  34. Ari Z, Aytekin M, Yigitoglu MR, Uyanik BS, Yar B.: Total CK ve CK-MB olcumlerinde kullanilan farkli yontemlerin analitik performanslarinin karsilastirilmasi. Ibni sina tip dergisi. 7, 171-176 (2002). CLICK TO DOWNLOAD PDF
  35. Aytekin M, Ari Z, Yigitoglu MR, Uyanik BS, Yar B. : Elecktrophoretic analysis of total creatine kinase and creatine kinase isoenzymes in hemodialysis patients. The Journal of Clinical Laboratory Research. (Klinik Laboratuar Arastirma Dergisi) (2001) 5, 23-27. CLICK TO DOWNLOAD PDF
  36. Yigitoglu MR, Uyanik BS, Ari Z, Akyildiz M, Aytekin M, Yar B : The relationship between serum sex hormones and bone non-bone alkaline phosphatase in healthy adults. The Journal of Clinical Laboratory Research. (Klinik Laboratuar Arastirma Dergisi)2, 87-94 (1998). CLICK TO DOWNLOAD PDF